100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
Subcutaneous (SC) Injection:
Low body weight considerations:
For IV Administration:
Measurement of dose:
Abdominal Surgery
- Dose: 40 mg SC once daily.
- Timing: Initiate 2 hours preoperatively.
- Duration: Administer for 7-10 days, or up to 12 days, until the DVT risk is diminished.
Knee or Hip Replacement Surgery
Option 1:
- Dose: 30 mg SC every 12 hours.
- Timing: Start 12–24 hours postoperatively.
- Duration: Continue for 10 days to 35 days or until the DVT risk is reduced.
Option 2 (for hip replacement):
- Dose: 40 mg SC once daily.
- Timing: Initiate 9–15 hours preoperatively.
- Duration: Continue for 10 days to 35 days.
Medical Patients with Restricted Mobility
- Dose: 40 mg SC once daily.
- Duration: Administer for 6–11 days, or up to 14 days, until DVT risk diminishes.
Inpatient (With or Without Pulmonary Embolism)
- 1 mg/kg SC every 12 hours, OR
- 1.5 mg/kg SC once daily.
Outpatient (Without Pulmonary Embolism)
- Dose: 1 mg/kg SC every 12 hours.
Considerations:
- Initiate warfarin therapy within 72 hours of starting enoxaparin.
- Continue enoxaparin for at least 5 days and until the INR is between 2.0–3.0.
- Typical duration is 7 days, but up to 17 days has been used in trials.
- Dose: 1 mg/kg SC every 12 hours.
- Concomitant Therapy: Administer with aspirin (100–325 mg/day PO).
- Duration: Treat for 2–8 days; up to 12.5 days in trials.
Patients <75 Years Old
- Loading Dose: 30 mg IV bolus plus 1 mg/kg SC once (max 100 mg cumulative loading dose).
- Maintenance Dose: 1 mg/kg SC every 12 hours.
Patients ≥75 Years Old
- Dose: 0.75 mg/kg SC every 12 hours (max 75 mg/dose for the first two doses).
PCI (Percutaneous Coronary Intervention)
- If Last Dose <8 Hours Ago: No additional dosing.
- If Last Dose 8–12 Hours Ago: 0.3 mg/kg IV bolus.
- If Last Dose >12 Hours Ago: Use alternative anticoagulation (e.g., unfractionated heparin or full-dose LMWH).
Concomitant Therapy
- Administer with aspirin (75–325 mg/day) and a thrombolytic agent, if appropriate.
Duration
- The optimal duration is 8 days or until hospital discharge, whichever comes first.
Prophylaxis:
Deep Vein Thrombosis (DVT) Treatment:
Non-Q-Wave Myocardial Infarction (MI):
Acute STEMI:
Hypersensitivity:
Active Bleeding Disorders:
Recent Hemorrhagic Stroke:
Allergic Reactions:
Exercise caution in patients with the following conditions:
Platelet Monitoring:
Lactation:
Category: Not formally classified under the FDA's previous categories, but data suggest minimal risk.
Human Data:
High-Risk Pregnancies:
Bleeding Risks:
Counseling:
Excretion in Human Milk:
Considerations:
Recommendation:
Concurrent use with other anticoagulants (e.g., warfarin, and heparin) significantly increases the risk of bleeding.
Platelet Aggregation Inhibitors:
- Examples: Dipyridamole, clopidogrel, ticlopidine, glycoprotein IIb/IIIa inhibitors.
- These agents impair platelet function, further increasing bleeding risk.
Salicylates and NSAIDs:
- Includes acetylsalicylic acid (aspirin) and other nonsteroidal anti-inflammatory drugs.
- Both classes can exacerbate gastrointestinal bleeding or inhibit platelet aggregation, heightening the risk.
Sulfinpyrazone:
- May potentiate bleeding tendencies when combined with enoxaparin.
Store in a cool and dry place, protect from light and moisture. Do not store above 25°C. Do not store in a refrigerator or freezer. Keep out of the reach of children
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.